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gtl-1

Gene

1 paper studies it1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Japan Society for the Promotion of Science
  • Model organisms1

Effects

1

Reactive oxygen species

downin worms1

1 study

  1. gtl-1 decreases reactive oxygen species in worms.

    “Knockdown of gtl-1, encoding Mg2+-incorporating channel into intestinal cells, reduced ROS levels and restored life span”

    Model organismsin intestinal cells of CNNM mutant wormsintestine

    Excessive Mg²⁺ Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species

    Antioxidants & redox signaling

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