GM5532

1 paper2 findings

1 lab in 1 country

Funder: National Natural Science Foundation of China

Animals1

Effects

2

Labile iron pool

upin mouse cells1

1 study

GM5532 increases labile iron pool in mouse cells.
“This cascade reduces the intracellular labile iron pool.”
Cellsshown by Gm5532 KO
LncRNA-Gm5532 deficiency alleviates bone resorption by inhibiting mitochondrial respiration through iASPP/NRF2
Cell biology and toxicology4 Feb 2026

More on Labile iron pool

Bone loss

upin mice1

1 study

GM5532 increases bone loss in mice.
“Gm5532 KO alleviates bone loss in aged, ovariectomized, and iron-overloaded mice by reducing osteoclast formation and activity.”
Animalsin aged, ovariectomized, and iron-overloaded mice
LncRNA-Gm5532 deficiency alleviates bone resorption by inhibiting mitochondrial respiration through iASPP/NRF2
Cell biology and toxicology4 Feb 2026

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Cell Biology and Toxicology4 Feb

LncRNA-Gm5532 deficiency alleviates bone resorption by inhibiting mitochondrial respiration through iASPP/NRF2

Experiments in miceNRF2–KEAP1 antioxidant response