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FRATAXIN

There is 1 paper on FRATAXIN in aging research: 1 observational study in people.

Gene

1 paper studies it1 finding

See all 1 papers on FRATAXIN

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“Protein levels of mitoferrin and frataxin were, respectively, higher and lower in the LF group relative to young participants and older adults with SPPB scores ≥ 11”
Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older AdultsCells2020doi:10.3390/cells9122579
Humans: a single group. Cells, worms or flies and mice: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Innovative Medicines Initiative and 3 more
  • Humans1

Associations

1

Low physical performance

downin humans1

1 study

  1. FRATAXIN is associated with low physical performance in humans (low-functioning older adults (SPPB ≤7) versus young and high-functioning (SPPB ≥11)).

    “Protein levels of mitoferrin and frataxin were, respectively, higher and lower in the LF group relative to young participants and older adults with SPPB scores ≥ 11”

    Humanslow-functioning older adults (SPPB ≤7) versus young and high-functioning (SPPB ≥11)skeletal muscle

    Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults

    Cells

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