FOXF2

1 paper1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care and 3 more

Cells1

Effects

1

Senescence-associated secretory phenotype (SASP)

upin human cells1

1 study

FOXF2 activates senescence-associated secretory phenotype (SASP) in human cells.
“FOXF1/2 interact with p300/CREB-binding protein (CBP) and stimulate H3K27 acetylation and chromatin opening at de novo enhancers of pro-inflammatory SASP genes”
Cellsin senescent cells
FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype
Molecular cell16 Apr 2026

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Molecular Cell18 Apr

FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype

Experiments in human cellsSenescence-associated secretory phenotype (SASP)