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fdps-1

Gene

1 paper studies it1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Army Research Office and others
  • Model organisms1

Effects

1

Healthspan

is required forin worms1

1 study

  1. fdps-1 is required for healthspan in worms (278 ± 9 vs. 894 ± 17%).

    “Genes required for ZA-mediated healthspan extension included fdps-1/FDPS-1 (278 ± 9 vs. 894 ± 17% population activity AUC in knockdown + 1 μM ZA vs. untreated controls, respectively, P < 0.0001)”

    Model organismsknockdown + 1 μM ZA vs. untreated controls

    Bisphosphonates attenuate age-related muscle decline in Caenorhabditis elegans

    Journal of cachexia, sarcopenia and muscle

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