There is 1 paper on ecps-2 in aging research: none in people yet, 1 in animals.
At a glance
The findings reach worms or flies, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
Worms or flies: a single group. Cells, mice and humans: nothing yet.
- 1 lab in 1 country
- Funders: Glenn Foundation for Medical Research and 6 more
- Model organisms1
Effects
2Proteostasis
is required forin worms1
1 study
Proteostasis
is required forin worms1
ecps-2 is required for proteostasis in the rpn-10 mutant.
“We further show that ecps-2 is required for improved ER proteostasis as well as lifespan extension of the rpn-10 mutant”
Model organismsin the rpn-10 mutant
Biochimica et biophysica acta. Gene regulatory mechanisms
Lifespan
is required forin worms1
1 study
Lifespan
is required forin worms1
ecps-2 is required for lifespan in the rpn-10 mutant.
“We further show that ecps-2 is required for improved ER proteostasis as well as lifespan extension of the rpn-10 mutant”
Model organismsin the rpn-10 mutant
Biochimica et biophysica acta. Gene regulatory mechanisms
Latest
Biochimica et Biophysica Acta Gene Regulatory Mechanisms
A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant
Experiments in wormsUbiquitin–proteasome system