ATZ reporter accumulation

There is 1 paper on ATZ reporter accumulation in aging research: none in people yet, 1 in animals.

1 paper studies it1 finding

See all 1 papers on ATZ reporter accumulation

Model organisms1

Upstream

1

rpn-10

downin worms1

1 study

rpn-10 decreases ATZ reporter accumulation in rpn-10 mutant C. elegans alpha-1 antitrypsin deficiency model.
“The rpn-10 mutant shows a significant reduction in the accumulation of the ATZ reporter, thus indicating that its ER proteostasis is augmented”
Model organismsin rpn-10 mutant C. elegans alpha-1 antitrypsin deficiency modelintestine
A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant
Biochimica et biophysica acta. Gene regulatory mechanismsJun 22, 2023

Latest

Biochimica et Biophysica Acta Gene Regulatory MechanismsJun 25

A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant

Experiments in wormsUbiquitin–proteasome system