There are 3 papers on XBP-1 splicing in aging research: none in people yet, 3 in animals.
3 papers study it1 more mentions it1 finding
See all 4 papers on XBP-1 splicing
- Animals2
- Model organisms1
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1Oxidative stress and ROS signaling
downin mice1
1 study
Oxidative stress and ROS signaling
downin mice1
Oxidative stress and ROS signaling decreases XBP-1 splicing in mice (high oxidation, ER stress).
“high levels of oxidation increased ER stress-induced cell death and decreased IRE1 levels and XBP-1 splicing”
Animalshigh oxidation, ER stress
Excessive Oxidative Stress Contributes to Increased Acute ER Stress Kidney Injury in Aged Mice
Oxidative medicine and cellular longevity
Latest
Biochimica et Biophysica Acta Gene Regulatory Mechanisms
A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant
Experiments in wormsUbiquitin–proteasome system
Redox Biology
The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction
Experiments in miceMechanisms
Oxidative Medicine and Cellular Longevity
Excessive Oxidative Stress Contributes to Increased Acute ER Stress Kidney Injury in Aged Mice
Experiments in miceER unfolded protein response
Nature Aging
Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation
Experiments in wormsTGF-β signaling