The Journal of Clinical Investigation
Patient muscles show early signs of cell senescence
An analysis of patient muscle gene activity found senescence-related patterns linked to disease severity and present even without inflammation visible on scans.An analysis of patient muscle gene activity found senescence-related patterns linked to disease severity and present even without inflammation visible on scans.
Cross-sectional studyCellular senescence
Who was studiedPeople with facioscapulohumeral muscular dystrophy
What changedSenescence-related gene-activity patterns appeared even in patient muscles without inflammation visible on scans
The catchPatient findings used senescence-related gene-activity patterns as a proxy for cellular senescence