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DCLRE1B

Gene

3 papers study it2 findings

HGNCNCBI GeneTaxon

See all 3

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 2 independent labs in 3 countries
  • Funders: Broad Institute and others
  • 2 of 2 findings with company ties
  • Humans2
  • In silico1

Associations

2

Type 1 diabetes

upin humans1

1 study

  1. DCLRE1B is associated with type 1 diabetes in humans.

    “analysis of sQTLs also reveals candidate effector genes for T1D susceptibility such as DCLRE1B, a senescence regulator, and lncRNA MEG3.”

    Humanspancreatic islets

    Genetic regulation of RNA splicing in human pancreatic islets

    Genome biology

More on Type 1 diabetes

Telomere length

upin humans1

1 study

  1. DCLRE1B is associated with telomere length in humans.

    “Using a multi-variant gene-based approach, we identified two genes newly implicated in telomere length, DCLRE1B (SNM1B) and PARN.”

    Humanswhole blood

    Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

    Cell genomics

More on Telomere length

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