CTHRC1

2 papers2 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: Huazhong University of Science and Technology and 1 more

Animals1
In silico1

Effects

2

Metastasis

upin human cells1

1 study

CTHRC1 increases metastasis in human cells.
“CTHRC1 was significantly elevated in SCAFs promoted cancer stemness and metastasis via the SRY-box transcription factor 4 (SOX4)-CTHRC1-Notch1 axis in HCC.”
Cellsvia SOX4-CTHRC1-Notch1 axis
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma
Cell communication and signaling : CCS25 Aug 2025

Cancer stemness

upin human cells1

1 study

CTHRC1 increases cancer stemness in human cells.
“CTHRC1 was significantly elevated in SCAFs promoted cancer stemness and metastasis via the SRY-box transcription factor 4 (SOX4)-CTHRC1-Notch1 axis in HCC.”
Cellsvia SOX4-CTHRC1-Notch1 axis
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma
Cell communication and signaling : CCS25 Aug 2025

Latest

1 in 12 months

Recent Patents on Anti-cancer Drug Discovery21 Jul

Molecular Mechanisms and Senescence Signatures in Cervical Squamous Cell Carcinoma: Insights from Transcriptomic and Single-cell Analyses

Computational studyCellular senescence

Cell Communication and Signaling28 Aug

Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma

Experiments in miceCellular senescence