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CRERECOMBINASE

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Erasmus+
  • 1 of 1 finding with company ties
  • Cells1

Effects

1

Provirus excision

upin human cells1

1 study

  1. CRERECOMBINASE increases provirus excision in human cells (>90%).

    “Transient expression of Cre recombinase, delivered by transfection or adenoviral vector transduction, allowed excision of the entire provirus with up to >90% efficiency.”

    Cellsdelivered by transfection or adenoviral vector transduction

    Reversible immortalization of human myogenic cells by site-specific excision of a retrovirally transferred oncogene

    Human gene therapy1 Jul 1999

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