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CREG1

Gene

2 papers2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Akiyama Life Science Foundation and 4 more
  • Humans1
  • Animals1

Effects

1

Lifespan

downin mice1

1 study

  1. CREG1 shortens lifespan in mice.

    “the average lifespan of adipocyte P2-CREG1 transgenic (Tg) mice was shorter than that of WT mice.”

    Animalsadipocyte P2-CREG1 transgenic miceadipose tissue

    Aged mice overexpressing cellular repressor of E1A-stimulated genes 1 in adipose tissues exhibited increased liposarcoma incidence and shortened lifespan

    Biochemical and biophysical research communications6 Feb 2025

Associations

1

Liposarcoma

upin mice1

1 study

  1. CREG1 raises the risk of liposarcoma in mice.

    “this reduced lifespan was associated with an increased incidence of liposarcoma (LPS).”

    Animalsadipocyte P2-CREG1 transgenic micewhite adipose tissue

    Aged mice overexpressing cellular repressor of E1A-stimulated genes 1 in adipose tissues exhibited increased liposarcoma incidence and shortened lifespan

    Biochemical and biophysical research communications6 Feb 2025

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