GRIK2

2 papers1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: Army Research Office and others

Humans1
Animals1

Associations

1

Longevity

upin humans1OR 1.24

1 study

GRIK2 is associated with longevity in humans (OR 1.24, p = 5.09 × 10(-8)).
“we found suggestive evidence for the association of SNPs near CADM2 (odds ratio [OR] = 0.81; p value = 9.66 × 10(-7)) and GRIK2 (odds ratio = 1.24; p value = 5.09 × 10(-8)) with longevity.”
Humans
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy
The journals of gerontology. Series A, Biological sciences and medical sciences8 Sep 2014

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Experimental Neurology12 Dec

Loss of presenilin 2 function age-dependently increases susceptibility to kainate-induced acute seizures and blunts hippocampal kainate-type glutamate receptor expression

Experiments in miceMechanisms

The Journals of Gerontology, Series A8 Sep

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

Study of 6,036 peoplePopulations