Terbinafine

  • 1 lab in 1 country
  • Funders: Amsterdam University Medical Centers and 6 more
  • Model organisms1

Outcomes

3

atfs-1

upin worms1

1 study
  1. Terbinafine activates atfs-1 in worms.

    “Terbinafine and miglustat robustly activated the mitochondrial unfolded protein response (UPRmt) mediator ATFS-1”

    Model organisms

    Targeting Mitochondrial Stress Responses: Terbinafine and Miglustat as Novel Lifespan and Healthspan Modulators

    Aging cell31 Mar 2026

More on atfs-1

Healthspan

upin worms1

1 study
  1. Terbinafine improves healthspan in worms.

    “we identify terbinafine and miglustat as novel mitochondrial stress inducers that extend lifespan and improve healthspan in Caenorhabditis elegans.”

    Model organisms

    Targeting Mitochondrial Stress Responses: Terbinafine and Miglustat as Novel Lifespan and Healthspan Modulators

    Aging cell31 Mar 2026

Lifespan

upin worms1

1 study
  1. Terbinafine extends lifespan in worms.

    “we identify terbinafine and miglustat as novel mitochondrial stress inducers that extend lifespan and improve healthspan in Caenorhabditis elegans.”

    Model organisms

    Targeting Mitochondrial Stress Responses: Terbinafine and Miglustat as Novel Lifespan and Healthspan Modulators

    Aging cell31 Mar 2026

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