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AstC

Gene

1 paper studies it2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Danmarks Frie Forskningsfond and 8 more
  • Model organisms1

Effects

2

Lipid and sugar mobilization

upin flies1

1 study

  1. AstC improves lipid and sugar mobilization in flies.

    “Loss of gut Allatostatin C or its receptor in the adipokinetic-hormone-producing cells impairs lipid and sugar mobilization during fasting, leading to hypoglycemia.”

    Model organismsduring fasting

    The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

    Nature communications

Glucagon-like adipokinetic hormone secretion

upin flies1

1 study

  1. AstC induces glucagon-like adipokinetic hormone secretion in flies.

    “Gut-derived allatostatin C induces secretion of glucagon-like adipokinetic hormone to coordinate food intake and energy mobilization.”

    Model organismsunder nutrient stressgut

    The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

    Nature communications

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