Vascular stiffening

1 paper

Humans1

Funding

1 grant since 2023

National Heart, Lung, and Blood InstituteUS$517.3k

Lysyl Oxidase Like 2: A Novel Target in Aging Associated Vascular Stiffening
National Heart, Lung, and Blood InstituteJohns Hopkins UniversityUS$111.4k2020–2025

Latest

5 in 12 months

bioRxiv2 Feb

Stiffness Drives Endothelial Senescence and Inflammation in Aging and Doxorubicin-Induced Vascular Dysfunction

Preprint: experiments in cellsMechanisms

Geriatric Nursing23 Jan

Intracranial compliance is influenced by sex in older adults

Cross-sectional study of 187 peopleBiomarkers

npj Aging21 Nov

Prolonged intermittent hypoxia accelerates cardiovascular aging and mortality: insights from a murine model of OSA

Experiments in miceHypoxia and HIF signalling

bioRxiv19 Nov

Age-Related Decline in NCKX4-Mediated Calcium Clearance Accelerates Aortic Remodeling and Drives Early Vascular Aging

Preprint: experiments in miceExtracellular matrix remodelling

medRxiv17 Nov

A photoplethysmography-based aging clock reveals genetic determinants of arterial aging

Preprint: cohort study of 114,098 peopleBiomarkers

AHA Scientific Sessions 2025 Abstract3 Nov

Plasminogen Activator Inhibitor-1 Governs Arterial Aging

Experiments in miceMechanisms

The Journal of Cardiovascular Aging1 Jan

Declining nitric oxide bioavailability in cardiovascular aging: mechanistic insights and emerging interventions

ReviewMechanisms

Aging Cell7 Mar

Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response

Experiments in miceDNA repair