Severe pain

There are 6 papers on severe pain in aging research: 5 observational studies in people, 1 review. The newest story, Nov 2, 2026: “Joint, back and shoulder pain followed two paths with age”.

Disease

6 papers study it153 more mention it1 finding

5 new papers in 30 daysSee all 159 papers on severe pain

“Total life expectancy varies only slightly by baseline pain states but pain-free life expectancy varies greatly.”
Life Expectancy With and Without Pain in the U.S. Elderly PopulationThe journals of gerontology. Series A, Biological sciences and medical sciences2016doi:10.1093/gerona/glw028
  • Humans5

Effects

1

Pain-free life expectancy

downin humans1

1 study
  1. Severe pain is linked with lower pain-free life expectancy in humans (5.28 vs 2.66 years).

    “Total life expectancy varies only slightly by baseline pain states but pain-free life expectancy varies greatly.”

    Humansfemales

    Life Expectancy With and Without Pain in the U.S. Elderly Population

    The journals of gerontology. Series A, Biological sciences and medical sciences

Trial sponsors

  • EMS

    Company1 trialPhase 3252 people

Latest

Dec 2025: 8Jan 2026: 6Feb 2026: 4Mar 2026: 3Apr 2026: 2May 2026: 1Jun 2026: 4Jul 2026: 1Aug 2026: 1Sep 2026: 2Oct 2026: 4Nov 2026: 137 papers in 12 months
Pain

Joint, back and shoulder pain followed two paths with age

The high-risk group included 20% of women and 9% of men in a Swedish survey that followed 6,328 people for 42 years.The high-risk group included 20% of women and 9% of men in a Swedish survey that followed 6,328 people for 42 years.

Cohort · 6,328 peopleBones and joints

See all 159 papers on severe pain