Renal amyloid A amyloidosis

1. FAS raises the risk of renal amyloid A amyloidosis in mice (nearly 50%).

   “nearly 50% of the aged (>18-mo-old) Fas-Tg mice developed renal amyloid A amyloidosis, whereas no amyloid deposition was observed in aged non-Tg mice.”

   Animalsaged Fas-Tg micekidney

   Increased acute-phase response and renal amyloidosis in aged CD2-fas-transgenic mice

   Journal of immunology (Baltimore, Md. : 1950)·15 Jun 1997

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