Recurrent spontaneous abortion

Disease

4 papers5 findings

  • Humans2
  • Animals1
  • Cells1

Effects

4

Trophoblast function

downin humans1

1 study
  1. Recurrent spontaneous abortion impairs trophoblast function in humans.

    “In RSA villi, the functions of both CTBs and syncytiotrophoblasts were impaired.”

    Humansin RSA villiplacental villi

    Single-cell transcriptomics reveals cytotrophoblast subtypes and senescence in recurrent spontaneous abortion

    Reproduction (Cambridge, England)18 Mar 2026

TNRC6B

upin silico1

1 study
  1. Recurrent spontaneous abortion increases TNRC6B in silico.

    “Three cellular senescence genes-TBX2, SRSF3, and TNRC6B-were identified and found to be upregulated in RSA patients.”

    In silicoin RSA patients

    Identification and validation of cell senescence genes in recurrent spontaneous abortion via multiple bioinformatics algorithms

    Scientific reports10 Oct 2025

More on TNRC6B

SRSF3

upin silico1

1 study
  1. Recurrent spontaneous abortion increases SRSF3 in silico.

    “Three cellular senescence genes-TBX2, SRSF3, and TNRC6B-were identified and found to be upregulated in RSA patients.”

    In silicoin RSA patients

    Identification and validation of cell senescence genes in recurrent spontaneous abortion via multiple bioinformatics algorithms

    Scientific reports10 Oct 2025

More on SRSF3

TBX2

upin silico1

1 study
  1. Recurrent spontaneous abortion increases TBX2 in silico.

    “Three cellular senescence genes-TBX2, SRSF3, and TNRC6B-were identified and found to be upregulated in RSA patients.”

    In silicoin RSA patients

    Identification and validation of cell senescence genes in recurrent spontaneous abortion via multiple bioinformatics algorithms

    Scientific reports10 Oct 2025

More on TBX2

Associations

1

Cellular senescence

upin humans1

1 study
  1. Recurrent spontaneous abortion is associated with cellular senescence in humans.

    “Notably, CTB2 and CTB3 exhibited pronounced features of cellular senescence, potentially contributing to reduced proliferative and differentiation capacity.”

    Humansin RSA villiplacental villi

    Single-cell transcriptomics reveals cytotrophoblast subtypes and senescence in recurrent spontaneous abortion

    Reproduction (Cambridge, England)18 Mar 2026

More on Cellular senescence

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