What does the research say about Primary nonfunction?

Primary nonfunction

There are 3 papers on primary nonfunction in aging research: 1 trial and 2 observational studies in people.

3 papers study it2 more mention it2 findings

1 new paper in 30 daysSee all 5

“a lower incidence of primary nonfunction compared with the control group”

The efficacy of N-acetylcysteine as a hepatoprotective agent in liver transplantationTransplant international : official journal of the European Society for Organ Transplantation1998doi:10.1007/s001470050505

Elderly donor liver transplantation

upin humans1OR 3.199

1 study

Elderly donor liver transplantation is associated with primary nonfunction in humans (Adjusted analysis following deceased-donor liver transplantation) (Adjusted OR 3.199, 95% CI 2.131–4.802; incidence 4.0% versus 0.9%).
“After adjustment, elderly donor status remained associated with PNF (odds ratio [OR], 3.199; 95% confidence interval [CI], 2.131-4.802)”
HumansAdjusted analysis following deceased-donor liver transplantationlivern = 950
Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study
Transplantation directOct 21, 2026

Acetylcysteine

downin humans1

1 study

Acetylcysteine lowers the risk of primary nonfunction in liver transplanted patients.
“a lower incidence of primary nonfunction compared with the control group”
Human trialin liver transplanted patientsliver
The efficacy of N-acetylcysteine as a hepatoprotective agent in liver transplantation
Transplant international : official journal of the European Society for Organ TransplantationJan 1, 1998