Elderly donor liver transplantation

Elderly donor liver transplantation has been studied in 1 paper since 2026: 1 observational study in people; 1 in the past year. The newest paper, Oct 21, 2026: “Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study”.

Exposure

1 paper studies it5 findingsUpdated

1 new paper in 30 daysSee all 1

“Overall survival (P = 0.681) and hepatocellular carcinoma disease-free survival (P = 0.486) were similar between groups.”
Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective StudyTransplantation direct2026doi:10.1097/txd.0000000000002018

None of its findings points the other way.

  • 1 lab in 1 country
  • Humans1

What did studies of Elderly donor liver transplantation find?

2

Studies of Elderly donor liver transplantation measured 2 outcomes; the most studied are hepatocellular carcinoma disease-free survival (1 study) and overall survival (1).

Hepatocellular carcinoma disease-free survival

no changein humans1

1 study
  1. Elderly donor liver transplantation was not clearly linked with hepatocellular carcinoma disease-free survival in humans (Liver transplantation for hepatocellular carcinoma).

    “Overall survival (P = 0.681) and hepatocellular carcinoma disease-free survival (P = 0.486) were similar between groups.”

    HumansLiver transplantation for hepatocellular carcinomaliver

    Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study

    Transplantation direct

Overall survival

no changein humans1

1 study
  1. Elderly donor liver transplantation was not clearly linked with overall survival in humans (Deceased-donor liver transplantation).

    “Overall survival (P = 0.681) and hepatocellular carcinoma disease-free survival (P = 0.486) were similar between groups.”

    HumansDeceased-donor liver transplantationlivern = 950

    Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study

    Transplantation direct

What is Elderly donor liver transplantation linked with?

3

Studies link Elderly donor liver transplantation with 3 measures, most often splenic artery steal syndrome (1 study), acute rejection (1) and primary nonfunction (1).

Splenic artery steal syndrome

upin humans1OR 5.881

1 study
  1. Elderly donor liver transplantation is associated with splenic artery steal syndrome in humans (Adjusted analysis following deceased-donor liver transplantation) (Adjusted OR 5.881, 95% CI 1.043–33.149; incidence 2.0% versus 0.5%).

    “Elderly donor grafts were not associated with inferior long-term recipient survival but were associated with higher risks of PNF, AR, and SASS.”

    HumansAdjusted analysis following deceased-donor liver transplantationlivern = 950

    Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study

    Transplantation direct

More on Splenic artery steal syndrome

Acute rejection

upin humans1OR 5.314

1 study
  1. Elderly donor liver transplantation is associated with acute rejection in humans (Adjusted analysis following deceased-donor liver transplantation) (Adjusted OR 5.314, 95% CI 1.720–16.420; incidence 29.4% versus 10.9%).

    “Elderly donor grafts were not associated with inferior long-term recipient survival but were associated with higher risks of PNF, AR, and SASS.”

    HumansAdjusted analysis following deceased-donor liver transplantationlivern = 950

    Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study

    Transplantation direct

More on Acute rejection

Primary nonfunction

upin humans1OR 3.199

1 study
  1. Elderly donor liver transplantation is associated with primary nonfunction in humans (Adjusted analysis following deceased-donor liver transplantation) (Adjusted OR 3.199, 95% CI 2.131–4.802; incidence 4.0% versus 0.9%).

    “After adjustment, elderly donor status remained associated with PNF (odds ratio [OR], 3.199; 95% confidence interval [CI], 2.131-4.802)”

    HumansAdjusted analysis following deceased-donor liver transplantationlivern = 950

    Impact of Elderly Donors on Patient Survival and Postoperative Complications in Liver Transplantation: A Retrospective Study

    Transplantation direct

More on Primary nonfunction

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