Prevalent advanced-stage chronic kidney disease

1. Total fluid intake is associated with prevalent advanced-stage chronic kidney disease in humans (log-OR -0.27; 95% CI -0.43 to -0.11).

   “Higher daily total fluid intake, within the ranges studied, was associated with slower eGFR decline and lower odds of prevalent advanced CKD”

   Reviewkidney

   Fluid Intake and Kidney Function: A Systematic Review and Dose-Response Meta-analysis

   American journal of nephrology·16 Oct 2026

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