Phenoconversion

Disease

1 paper1 finding

  • Humans1

Associations

1

Ferritin

upin humans1

1 study
  1. Ferritin raises the risk of phenoconversion in humans (hazard ratio 2.91, 95% CI 1.06-7.99).

    Humansin patients with iRBD4.06 ± 2.1 yearsn = 79

    Serum Ferritin and Inflammation in Isolated REM Sleep Behavior Disorder: A Longitudinal Study

    Neurology4 Aug 2026

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Sleep Medicine

Dopamine loss in sleep disorder predicts Parkinson conversion

In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward…In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward Parkinson's disease.

Cohort study of 194 peopleParkinson's disease
Journal of Neurology

Multimodal PET and MRI predict dementia with Lewy bodies

Combined occipito-parietal cortex pathology and striatal dopamine loss predicted conversion to dementia with Lewy bodies with a sub-distribution hazard ratio of 38.68.Combined occipito-parietal cortex pathology and striatal dopamine loss predicted conversion to dementia with Lewy bodies with a sub-distribution hazard ratio of 38.68.

Cohort study of 21 peopleDementia with Lewy bodies