AAIC 2025 Abstract

The Impact of Striatal Dopaminergic Deficits and Alpha‐Synucleinopathy on Cognitive Function in REM Sleep Behavior Disorder

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Abstract

Background: Presynaptic protein α‐synuclein (αSyn) plays a role in Alzheimer's disease (AD) and Parkinson's disease (PD) with evidence suggesting αSyn pathology preceding and driving striatal dopaminergic neurodegeneration in PD.

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