Pathologic cardiac hypertrophy

1 paper1 finding

Interventions

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Estrogen

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1 study

Estrogen decreases pathologic cardiac hypertrophy.
“Estrogen also attenuates pathologic cardiac hypertrophy.”
Review
Estrogen and the cardiovascular system
Pharmacology & therapeutics28 Mar 2012

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Experiments in ratsAerobic exercise

Journal of Translational Medicine12 Apr

GPR30-mediated NETs degradation via Trex1 in heart failure of aged female mice

Experiments in miceMechanisms

PNAS14 May

Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging

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Downregulation of MLF1 safeguards cardiomyocytes against senescence-associated chromatin opening

Experiments in animalsMechanisms

Advanced Biology22 May

Combined Endurance and Resistance Exercise Mitigates Age-Associated Cardiac Dysfunction

Experiments in animalsInterventions

Free Radical Research17 Apr

Calorie restriction anti-hypertrophic effects are associated with improved mitochondrial content, blockage of Ca²⁺-induced mitochondrial damage, and lower reverse electron transport-mediated oxidative stress

Experiments in animalsInterventions

Biochimica et Biophysica Acta Molecular Basis of Disease27 Aug

Upregulation of mitochondrial telomerase reverse transcriptase mediates the preventive effect of physical exercise on pathological cardiac hypertrophy via improving mitochondrial function and inhibiting oxidative stress

Experiments in animalsInterventions

Pharmacology & Therapeutics28 Mar

Estrogen and the cardiovascular system