Myofiber atrophy

1 paper1 finding

Animals1

Upstream

1

TERF2

upin mice1

1 study

TERF2 increases myofiber atrophy in mice.
“exhibit a younger muscle phenotype with lack of ongoing or past regeneration and myofiber atrophy”
Animalsshown by skeletal-myofiber-specific Terf2 knockoutskeletal myofiberfemales
Anti-aging effect of TRF2 inhibition in skeletal myofibers
Research Square5 Apr 2024Preprint

Latest

3 in 12 months

Frontiers in Immunology19 Sep

The ageing microenvironment in sarcopenia: early alterations and targeted therapeutic strategies

ReviewMuscle

Biochemical and Biophysical Research Communications24 Jun

CIRBP maintains skeletal muscle mitochondrial energy homeostasis via mt-ATP6 to ameliorate sarcopenia

Experiments in miceSarcopenia

Frontiers in Genetics22 Jan

Impact of exercise-induced DNA damage repair on age-related muscle weakness and sarcopenia

ReviewResistance training

Aging Cell30 Jul

Histone β-hydroxybutyrylation is critical in reversal of sarcopenia

Experiments in animalsInterventions

Research Square5 Apr

Anti-aging effect of TRF2 inhibition in skeletal myofibers

Preprint: experiments in miceMechanisms

Nature Communications3 Mar

Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging

Experiments in miceProteostasis

European Journal of Applied Physiology21 Mar

The senescent rat diaphragm does not exhibit age-related changes in caspase activities, DNA fragmentation, or myonuclear domain

Experiments in ratsMechanisms