1 finding
PAOPAC biological age
upin silico1
Majority of diseases are associated with PAOPAC biological age in silico.
“Our analyses revealed that the majority of diseases are associated with an accelerated aging phenotype.”
In silico
Proteome-aware organ proxy aging clocks
bioRxiv (Cold Spring Harbor Laboratory)28 Apr 2026Preprint
PM2.5 showed the strongest association, with a hazard ratio of 1.22 per 5 µg/m³ higher exposure in 313,534 UK Biobank participants.PM2.5 showed the strongest association, with a hazard ratio of 1.22 per 5 µg/m³ higher exposure in 313,534 UK Biobank participants.
In 48,645 UK Biobank participants, plasma proteomic profiles linked ambient air pollutants to mortality and chronic diseases through shared immune and divergent molecular…In 48,645 UK Biobank participants, plasma proteomic profiles linked ambient air pollutants to mortality and chronic diseases through shared immune and divergent molecular pathways.
In older veterans, primary kidney and survival risks matched with a hazard ratio of 1.00, though SGLT2 inhibitors showed lower sustained kidney decline and end-stage…In older veterans, primary kidney and survival risks matched with a hazard ratio of 1.00, though SGLT2 inhibitors showed lower sustained kidney decline and end-stage disease.