Knee/hip osteoarthritis risk

Disease

1 paper1 finding

  • Humans1

Associations

1

Pain-free status

downin humans1

1 study
  1. Pain-free status is associated with knee/hip osteoarthritis risk in humans.

    “MR confirmed that pain-free status was linked to a lower risk of knee/hip OA.”

    HumansMendelian randomization analysis

    Pain changes linked to osteoarthritis risk in older adults

    Research Square16 Oct 2026Preprint

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Research Square

Pain changes linked to osteoarthritis risk in older adults

An observational analysis of 67,374 adults aged 50 or older across five cohorts linked developing or recovering from pain to later osteoarthritis risk.An observational analysis of 67,374 adults aged 50 or older across five cohorts linked developing or recovering from pain to later osteoarthritis risk.

Preprint: cohort study of 67,374 adults aged ≥ 50 years without osteoarthritisPain

Limit: Self-reported diagnoses or medication use could misclassify incident osteoarthritis