Experimental Hematology
Gene loss impaired movement of immune cells from mice
In laboratory tests, immune cells from genetically altered mice moved less effectively toward a chemical signal than cells from control mice.In laboratory tests, immune cells from genetically altered mice moved less effectively toward a chemical signal than cells from control mice.
Animal cell studyImmune response
Who was studiedBone marrow neutrophils from mice, against wild-type controls
What changedBone marrow neutrophils lacking Dnmt3a showed impaired migration compared to wild-type controls
The catchVav-Cre mice carry a Commd10 mutation that may independently alter inflammatory responses