Incident coronary heart disease, heart failure, stroke, or invasive cancer

1. IL6R has no effect on incident coronary heart disease, heart failure, stroke, or invasive cancer in humans.

   “The risks of CHD, HF, stroke, or cancer did not differ among IL6R variant carriers.”

   HumansPostmenopausal women; IL6R rs8192284 carrier statusMedian follow-up of 20 yearsfemalesn = 38,807

   Genetic interleukin-6 receptor blockade, chronic disease risk, and longevity: results from the women's health initiative

   European journal of preventive cardiology·17 Jul 2025

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