Homozygous familial hypercholesterolemia

Disease3 papers1 finding

Humans1

Effects

1

Lifespan

downin humans1

1 study

Homozygous familial hypercholesterolemia shortens lifespan in humans.
Reviewhomozygous familial hypercholesterolemia
Familial Hypercholesterolemia · Methodist DeBakey cardiovascular journal · 15 Sep 2026

Trial sponsors

Regeneron
Company4 trialsPhase 3270 people
AstraZeneca
Company2 trialsPhase 329 people
Novartis
Company1 trialPhase 33,275 people
LIB Therapeutics
Company1 trialPhase 365 people
Amgen
Company1 trialPhase 2/358 people
Akeso
Company1 trialPhase 210 people
Daniel Gaudet
1 trialPhase 310 people

Latest

3

Methodist DeBakey Cardiovascular JournalReview19 Sep

Familial Hypercholesterolemia

Journal of Clinical LipidologyHumans17 Sep

Predictors of aortic stenosis in homozygous familial hypercholesterolemia: A study from the Canadian HoFH registry

JACC Case ReportsResearch10 Sep

Early Coronary Atherosclerosis in Homozygous Familial Hypercholesterolemia: The Importance of Aggressive Lipid Lowering

Atherosclerosis