Fertility disorders

1 paper

Model organisms1

Trial sponsors

Leiden University Medical Center
1 trialPhase 4490 people
Hospital de Clinicas de Porto Alegre
1 trialPhase 326 people
Aalborg University Hospital
1 trialPhase 280 people

Latest

2 in 12 months

ReproductionJan 23

High dietary fructose induces the senescence of granulosa cells by enhancing O-GlcNAcylation

Experiments in miceCellular senescence

Nature CommunicationsNov 20

PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy

Experiments in miceMechanisms

AntioxidantsDec 31

Nicotinamide Mononucleotide Restores NAD⁺ Levels to Alleviate LPS-Induced Inflammation via the TLR4/NF-κB/MAPK Signaling Pathway in Mice Granulosa Cells

Experiments in mouse cellsNicotinamide mononucleotide

Aging and DiseaseSep 26

NAD⁺ Metabolism and Mitochondrial Activity in the Aged Oocyte: Focus on the Effects of NAMPT Stimulation

Experiments in mouse cellsInterventions

Aging CellDec 4

Single-cell transcriptome characteristics of testicular terminal epithelium lineages during aging in the Drosophila

Experiments in fliesMechanisms

AgingMay 23

Impaired telomere pathway and fertility in Senescence-Accelerated Mice Prone 8 females with reproductive senescence

Experiments in miceTelomerase and telomere maintenance

Frontiers in EndocrinologyOct 2

Role of AMH in Prediction of Menopause

ReviewBiomarkers

BiomedicinesJul 20

Ovarian Telomerase and Female Fertility

ReviewMechanisms

TheriogenologyNov 27

Influence of the age of the individual on the stability of boar sperm genetic material

Experiments in animalsMechanisms