Early gestational diabetes mellitus

1. HOMA-IR predicts early gestational diabetes mellitus in humans (AUROC 0.71 (95% CI 0.68-0.74)).

   “AUROC was significantly higher for eGDM than lGDM (0.71 (95% CI 0.68-0.74) vs 0.60(0.56-0.64)).”

   Human trialearly pregnancy HOMA-IRfemalesn = 1,225

   Early Insulin Resistance Is a Stronger Predictor of Early than Late Gestational Diabetes

   ADA Scientific Sessions 2026 abstract·5 Jun 2026

More on HOMA-IR

1. insulin resistance raises the risk of early gestational diabetes mellitus in humans (aOR 2.03 (1.69-2.42)).

   “adjusted OR 2.03(1.69-2.42)”

   Human trialper 1-SD increase in log-HOMA, adjusted for confoundersfemalesn = 1,225

   Early Insulin Resistance Is a Stronger Predictor of Early than Late Gestational Diabetes

   ADA Scientific Sessions 2026 abstract·5 Jun 2026