Papers on disequilibrium

214 papers18 new in 30 days

Friday, March 20

Journal of Cardiothoracic SurgeryMar 20

Causal inference and mediating pathways of metabolic syndrome on calcific aortic valve stenosis: linkage disequilibrium score regression and two-sample, two-step mendelian randomization study

Mendelian randomization in peopleCalcific aortic valve stenosis

Paper

Wednesday, March 11

arXivMar 11

SNPgen: Phenotype-Supervised Genotype Representation and Synthetic Data Generation via Latent Diffusion

Preprint: computational studyAI & data

Paper

Friday, March 6

MedicineMar 6

The causal relationship and metabolic mediation between telomere length and intervertebral disc degeneration: A two-stage network Mendelian randomization study

Computational studyTelomere length

Paper

Saturday, February 21

FASEB JournalFeb 21

Aging-Driven Inter-Organ Crosstalk in Postmenopausal Osteoporosis: From Immunometabolic Drift to Multisystem Frailty

ReviewBones and joints

Paper

Thursday, February 12

Archives of Medical ScienceFeb 12

Visual impairment and frailty: insights from genetic correlation and Mendelian randomization

Mendelian randomization in peopleVisual impairment

Paper

Saturday, January 24

MedicineJan 24

Causal association between sarcopenia and iron deficiency anemia: A two-sample Mendelian randomization study

Computational studyMechanisms

Paper

Monday, January 19

Genetic EpidemiologyJan 19

A Linear Mixed Model With Measurement Error Correction (LMM-MEC): A Method for Summary-Data-Based Multivariable Mendelian Randomization

Computational studyAI & data

Paper

Thursday, January 8

AAIC 2025 AbstractJan 8

Deep‐Block: Large‐scale WGS Analysis for Alzheimer's Disease Risk Variant Detection Using Deep Learning

Computational studyAlzheimer's disease

Paper

Friday, January 2

International Journal of SurgeryJan 2

Early-life tobacco exposure, genetic susceptibility, and multiple digestive diseases: evidence from two large cohorts and genetic analyses

Cohort study in peoplePopulations

Paper

Friday, December 26

Current Eye ResearchDec 26

Genetic Correlation and Mendelian Randomization Analyses Reveal Causal Links Between Metabolic-Associated Diseases or Risk Factors and Major Eye Diseases

Computational studyMechanisms

Paper

Wednesday, December 24

AAIC 2025 AbstractDec 24

Common genetic variants in HIVEP3 are associated with cognitive SuperAging in the Amish

Genetic association study of 515 peoplePopulations

Paper

Wednesday, December 3

Journal of Affective DisordersDec 3

Unraveling the genetic interplay between sleep disorders and Alzheimer's disease: From shared genes to potential therapeutic targets

Computational studyMechanisms

Paper

Monday, December 1

ZenodoDec 1

Multi-omic-deep-learning-identifies-exercise-responsive-ageing-pathways-in-humans

Preprint: computational studyDNA damage response

Paper

Monday, November 24

Brain and BehaviorNov 24

Comprehensive Genome-Wide Analysis of Shared Genetic Factors in Gastrointestinal and Neurodegenerative Diseases

Computational studyMechanisms

Paper

Thursday, November 20

MedicineNov 20

Causal effect between systemic inflammatory cytokines and osteoporotic pathological fractures: A bidirectional Mendelian randomization study

Study in peopleMechanisms

Paper

Saturday, November 8

MedicineNov 8

Association between frailty and gout in middle-aged and older adults: A nationwide cross-sectional and Mendelian randomization study

Mendelian randomization in 22,324 peopleGout

Paper

Thursday, November 6

Journal of Translational MedicineNov 6

Integrating genetics and transcriptome analyses identify potential biomarkers and immune interactions in metabolic syndrome-related sarcopenia

Experiments in animalsImmune response

Paper

Journal of Bone and Mineral MetabolismNov 6

Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies

Cohort study in peopleOsteoporosis

Paper

Monday, November 3

AHA Scientific Sessions 2025 AbstractNov 3

Brisk Usual Walking Pace Causally Remodels Brain, Heart and Metabolic Tissues

Mendelian randomization in 100,000 peopleMechanisms

Paper

Friday, September 26

The Journal of Nutritional BiochemistrySep 26

Metals exposure, biological aging and metabolic syndrome: exploring the associations and mediation effects

Cross-sectional study of 1,504 peopleMetabolic syndrome

Paper

Thursday, August 28

BiogerontologyAug 28

Genetic influence of the brain on epigenetic age acceleration: evidence of a large-scale genetic correlation study

Computational studyMechanisms

Paper

Wednesday, August 13

Computational and Structural Biotechnology JournalAug 13

Role of ferroptosis-related IREB2 in the shared genetic etiology between smoking and facial aging: Insights from large-scale genome-wide cross-trait analysis

Genetic association study in peopleMechanisms

Paper

Tuesday, July 22

Aging Clinical and Experimental ResearchJul 22

Sedentary lifestyle, physical activity, and aging: evidence from genetic correlation and mendelian randomization

Mendelian randomization in peoplePopulations

Paper

Monday, July 14

Addiction BiologyJul 14

Leveraging Genomic Data to Examine the Causal Impact of Alcohol, Tobacco, Cannabis, and Opioid Use on Biological and Cognitive Ageing

Computational studyPopulations

Paper

Thursday, July 3

Journal of Affective DisordersJul 3

The causal and mediated relationships between major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders and premature mortality: Evidence from genome-wide association study

Mendelian randomization in peoplePost-traumatic stress disorder

Paper

Tuesday, July 1

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za ZhiJul 1

Multi-omics Mendelian randomization study on the causality between non-ionizing radiation and facial aging

Mendelian randomization in 423,999 peoplePopulations

Paper

Saturday, June 28

Experimental Eye ResearchJun 28

Elucidating the genetic and metabolomic underpinnings of age-related macular degeneration through two-sample Mendelian randomization

Mendelian randomization in peopleEye

Paper

Saturday, June 21

Behavioural Brain ResearchJun 21

The shared genetic structure and causal analysis between frailty and suicide

Mendelian randomization in peopleMechanisms

Paper

Monday, June 16

Food Science & NutritionJun 16

Genetic Correlation and Mendelian Randomization Analyses Support Causal Relationships Between Instant Coffee and Age-Related Macular Degeneration

Mendelian randomization in peopleAge-related macular degeneration

Paper

Friday, June 13

ADA Scientific Sessions 2025 AbstractJun 13

Leveraging Rare Variant Association Analyses to Develop Polygenic Risk Scores (PRSs) for Type 2 Diabetes (T2D)

Genetic association study in peopleType 2 diabetes

Paper