Common variable immunodeficiency

2 papers1 finding

Human trial1
Humans1

Effects

1

Cxcl13

upin humans1

1 study

Common variable immunodeficiency increases Cxcl13 in humans.
“Plasmatic CXCL13 levels were elevated in this group”
Humansin CVID patients with autoimmunity
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency
European journal of immunologyMay 15, 2022

Trial sponsors

National Cancer Institute
2 trialsPhase 2137 people
Avni Joshi
1 trialPhase 220 people

Latest

1 in 12 months

Frontiers in ImmunologyJun 22

SLy1-deficiency results in functional impaired, exhausted and senescent NK cells

Experiments in miceCellular senescence

Brain, Behavior, & Immunity - HealthJan 27

Indications for an antidepressive effect of thymosin alpha-1 in a small open-label proof of concept study in common variable immune deficiency patients with depression

Non-randomized trial in 5 peopleDepression

European Journal of ImmunologyMay 15

Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency

Cohort study of 4 peopleApoptosis