1 paper2 findings
Perceived social support
downin humans1−1.7% attenuation
Perceived social support lowers the risk of cognitive impairment and dementia in humans (1.7% attenuation).
“Perceived social support slightly attenuates this association by 1.7%, with friendships accounting for 65.6% of the attenuation.”
Humansdriving cessation-induced risk
AAIC 2025 abstract25 Dec 2025
Driving cessation
upin humans1+34%
Driving cessation raises the risk of cognitive impairment and dementia in humans (+33.6%).
“Driving cessation is associated with a 33.6% increase in the probability of cognitive impairment and dementia.”
Humans
AAIC 2025 abstract25 Dec 2025
National Institute on AgingUS$30.6m
Smartphone-Based Solutions for Prospective Memory in Mild Cognitive Impairment and Dementia
National Institute on AgingBaylor UniversityUS$704k2023–2029
National Institute on AgingUniversity of Wisconsin-madisonUS$7.4m2021–2027
Deep learning for prediction of Mild Cognitive Impairment and Dementia of the Alzheimer's type
National Institute on AgingUniversity of Michigan at Ann ArborUS$185k2023–2026
Imaging Cerebral Small Vessels in Vascular Cognitive Impairment and Dementia (VCID)
National Institute on AgingUniversity of Southern CaliforniaUS$2.5m2023–2026
GPR39 as a Therapeutic Target in Aging-Related Vascular Cognitive Impairment and Dementia
National Institute on AgingOregon Health & Science UniversityUS$2.2m2023–2026
Role of Liver Fibrosis in Cognitive Impairment and Dementia
National Institute on AgingWeill Medical Coll of Cornell UnivUS$194.9k2021–2023
National Institute on AgingNational Institute on AgingUS$216.4k
Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.
A 20-year longitudinal study finds earlier family bereavement is tied to higher cognitive impairment risk, with child loss remaining robust after health adjustments.A 20-year longitudinal study finds earlier family bereavement is tied to higher cognitive impairment risk, with child loss remaining robust after health adjustments.
In 4,464 cognitively normal older adults, a higher immune risk score predicted incident cognitive impairment or dementia with a hazard ratio of 1.63 over six years.In 4,464 cognitively normal older adults, a higher immune risk score predicted incident cognitive impairment or dementia with a hazard ratio of 1.63 over six years.
In 218 responders and controls aged 44 to 65, cortical thickness was associated with the WTC exposure severity index at R = -0.38.In 218 responders and controls aged 44 to 65, cortical thickness was associated with the WTC exposure severity index at R = -0.38.