Perceived social support

3 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 1 country

Humans3

Associations

Cognitive impairment and dementia

downin humans1−1.7% attenuation

1 study

Perceived social support lowers the risk of cognitive impairment and dementia in humans (1.7% attenuation).
“Perceived social support slightly attenuates this association by 1.7%, with friendships accounting for 65.6% of the attenuation.”
Humansdriving cessation-induced risk
Hitting the Brakes: Driving Cessation, Cognitive Health, and the Mediating Role of Social Relationships Among Older Adults in the US
AAIC 2025 abstract25 Dec 2025

More on Cognitive impairment and dementia

Auditory working memory

downin humans1

1 study

Perceived social support is associated with auditory working memory in humans (β = -0.249, SE = 0.039, p = 0.001).
“worse auditory working memory ( β = ‐0.249, SE = 0.039, p = 0.001)”
Humansn = 141
Perceived Social Support and Cognitive Functions Among First‐Generation Older Asian Americans
AAIC 2025 abstract23 Dec 2025

Verbal encoding

upin humans1

1 study

Perceived social support is associated with verbal encoding in humans (β = 0.233, SE = 0.154, p = 0.003).
“Greater perceived social support was associated with better verbal encoding ( β = 0.233, SE = 0.154, p = 0.003)”
Humansn = 141
Perceived Social Support and Cognitive Functions Among First‐Generation Older Asian Americans
AAIC 2025 abstract23 Dec 2025