Cardiac conduction abnormalities

Disease

1 paper1 finding

  • Humans1

Associations

1

DMPKREPEATEXPANSIONS

upin humans1OR 4.86

1 study
  1. DMPKREPEATEXPANSIONS is associated with cardiac conduction abnormalities in humans (OR 4.86, CI 3.38–6.79).

    HumansUK Biobank; pathogenic DMPK expansion defined as ≥50 repeatsn = 490,086

    Myotonic dystrophy gene changes found in 1 in 1,527 people

    Brain : a journal of neurology10 Oct 2026

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Brain

Myotonic dystrophy gene changes found in 1 in 1,527 people

Across 985,026 participants, disease-causing DNA expansions occurred in about 1 in 1,527, compared with earlier disease prevalence estimates of 1 in 3,000–8,000.Across 985,026 participants, disease-causing DNA expansions occurred in about 1 in 1,527, compared with earlier disease prevalence estimates of 1 in 3,000–8,000.

Genetic association study of 985,026 peoplePopulations