Biliary fibrosis

3 papers1 finding

Animals3

Upstream

1

TERT

downin mice1

1 study

TERT decreases biliary fibrosis in mice.
“Cholangiocyte-selective deletion of TERT in mice exacerbated fibrosis”
Animalscholangiocyte-selective deletionliver
Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis
JCI insightSep 14, 2023

Latest

1 in 12 months

Cellular and Molecular Gastroenterology and HepatologyApr 13

Mesothelin/Mucin 16 Signaling in Activated Portal Fibroblasts Drives the Development of Cholestatic Fibrosis and Hepatocellular Carcinoma in Aged Female Multidrug Resistance Protein 2 Knockout Mice

Experiments in miceTGF-β signalling

JCI InsightSep 14

Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis

Experiments in miceTelomerase and telomere maintenance

Aging and DiseaseJun 13

The inhibition of YAP Signaling Prevents Chronic Biliary Fibrosis in the Abcb4-/- Model by Modulation of Hepatic Stellate Cell and Bile Duct Epithelium Cell Pathophysiology

Experiments in miceLiver fibrosis

Frontiers in MedicineMay 7

The Emerging Role of Macrophages in Chronic Cholangiopathies Featuring Biliary Fibrosis: An Attractive Therapeutic Target for Orphan Diseases

ReviewMechanisms