Atrial fibrillation recurrence or persistence

1. Atrial fibrillation recurrence or persistence is associated with major bleeding in humans (aHR 1.87, 95%CI 1.01-3.45).

   “Participants with recurrent or persistent AF had a higher incidence of major bleeding events, even after adjustment for anticoagulation, age, and other cardiovascular risk factors (aHR 1.87, 95%CI 1.01-3.45).”

   Humansatrial fibrillationtwo-year52% malesn = 773

   Recurrence or persistence of atrial fibrillation is associated with frailty and adverse outcomes: the SAGE-AF cohort study

   BMC geriatrics·13 Jun 2026

1. Frailty is associated with atrial fibrillation recurrence or persistence in humans (aOR 1.52, 95%CI 1.03-2.25).

   “Baseline frailty or pre-frailty was significantly associated with higher odds of AF recurrence or persistence (aOR 1.52, 95%CI 1.03-2.25).”

   Humansatrial fibrillationtwo-year52% malesn = 773

   Recurrence or persistence of atrial fibrillation is associated with frailty and adverse outcomes: the SAGE-AF cohort study

   BMC geriatrics·13 Jun 2026

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