A cohort of 66,905 women followed for a median 13 years found no links to cardiovascular disease, dementia or osteoporosis-related fractures compared with keeping…A cohort of 66,905 women followed for a median 13 years found no links to cardiovascular disease, dementia or osteoporosis-related fractures compared with keeping ovaries.

Ovaries and severed fallopian tubes sit among paired hearts, brains, and thighbones, with similarly intact structures in blue-green and gray.

Cohort · 57,305 peoplePopulations

Paper

Frontiers in MicrobiologyNov 5

The Gut Microbiome in Skeletal Homeostasis and Osteoporosis: A Triangulation of Mechanistic, Clinical, and Mendelian Randomization Evidence

Accepted, not yet published: reviewCellular homeostasis

Paper

Journal of the American Medical Directors AssociationNov 5

Incidence, Temporal Trends, and Associated Characteristics of Hip Fracture in Long-Term Care Residents: A Population-Based Cohort Study in British Columbia

Cohort study of 33,739 peopleHip fracture

Paper

BMC Oral HealthNov 5

Metformin modulates alveolar bone parameters and gene expression in streptozotocin-induced type 2 diabetic rats

Schematic representation of the experimental timeline, including induction of T2DM by 10% fructose feeding followed by a single intraperitoneal injection of streptozotocin (STZ, 40 mg/kg), and the…

Experiments in 18 ratsMetformin

Paper

The Journal of Frailty & AgingNov 5

Associations of muscle function with recurrent and injurious falls in adults aged 50 years and older: A systematic review

Figure from The Journal of Frailty & Aging

Systematic review of observational studiesMuscle

Paper

DiagnosticsNov 5

Atopic Dermatitis and Bone Fragility: Osteoimmunological Pathways, Therapeutic Paradoxes, and Risk-Adapted Screening Across the Lifespan

ReviewAtopic dermatitis

Paper

Archives of OsteoporosisNov 5

Two or three births linked to lower osteoporosis risk

Osteoporosis hazard ratios—measures of relative risk—were 0.894 for two live births and 0.892 for three, compared with women with none.Osteoporosis hazard ratios—measures of relative risk—were 0.894 for two live births and 0.892 for three, compared with women with none.

$An intact dark blue-green femur sits among women with children, beside a smaller fractured gray femur surrounded by women standing alone.$

Cohort · 119,969 peopleOsteoporosis

Paper

Journal of Shoulder and Elbow ArthroplastyNov 5

Complication risks, implant survival, and functional outcomes after reverse total shoulder arthroplasty in elderly trauma patients: a competing risk analysis

Cohort study of 208 peopleInterventions

Paper

The Journal of Hand Surgery Asian-Pacific VolumeNov 5

Mortality Following Distal Radius Fractures in Older Adults

Meta-analysis of observational studiesBones and joints

Paper

Journal of Orthopaedic ScienceNov 5

CT-derived Hounsfield units of the acromion and scapular spine: Age- and sex-related associations and measurement reliability in adults

Figure from Journal of Orthopaedic Science

Cross-sectional study of 201 peopleBiomarkers

Paper

Research SquareNov 5

Falls, fractures, lean mass and age with GLP-1receptor agonists and tirzepatide: meta-analysis of 162 placebo-controlled trials andage-subgroup data for adults aged 75 years orolder

Study selection. (A) Placebo-controlled trials of GLP-1 receptor agonists or tirzepatide with adverse-event results posted on ClinicalTrials.gov (searched 31 October 2026).

Preprint: meta-analysis of randomized trialsGLP-1 receptor agonists

Paper

Research SquareNov 5

Interimplant femoral fractures: a heterogeneous fragility injury Fracture patterns, management, and outcomes of a consecutive series

$Classification of interimplant femoral fractures according to the position of the proximal and distal implants Fractures were classified according to whether the proximal (first letter) and distal…$

Preprint: cohort study of 45 peopleBones and joints

Paper

BMJ MedicineNov 5

Model predicts fall and delirium admissions in older adults

The model scored 0.794 in development and 0.721 in Welsh testing for distinguishing who would be hospitalized, though its risk estimates were not always accurate.The model scored 0.794 in development and 0.721 in Welsh testing for distinguishing who would be hospitalized, though its risk estimates were not always accurate.

$Upright faceless people gather beside an intact thigh bone, while a smaller gray group stands near a fractured bone and a hospital bed.$