XRCC1 foci

1. XRCC1 foci is associated with PARP1 in humans.

   “In human-aged skin, XRCC1 foci accumulate in the epidermal cells in correlation with a decline of PARP1”

   Humansepidermal cell

   Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells

   Nature communications·Jan 29, 2016

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