White matter hyperintensity distribution subtypes

WMH progression is associated with white matter hyperintensity distribution subtypes in humans.

“WMH progressors were closer to centroids of clusters 2 and 4, further from clusters 3 and 5”

Humansin UK Biobank participantsn = 4,332

Location patterns of white matter hyperintensities in a multi‐cohort study — generalisability, evaluation, and longitudinal progression

AAIC 2025 abstract·24 Dec 2025