Vimentin aggregates
1 paper1 finding
- Animals1
Upstream
1CALU
downin mice1
1 study
CALU
downin mice1
CALU decreases vimentin aggregates in mice.
“calumenin collaborates with the TRiC complex to facilitate proper vimentin folding and recruits the chaperonin subunit Chaperonin Containing TCP1 Subunit 2 (CCT2) to degrade misfolded vimentin aggregates.”
Animalslung
Calumenin prevents fibroblast senescence and lung aging by promoting vimentin proteostasis
Proceedings of the National Academy of Sciences of the United States of America20 Jan 2026