Urine sodium

1. Dapagliflozin showed no clear effect on urine sodium in dogs with heart disease (treatment effect, -41 mmol/L, P = .12).

   “but not for uNa (baseline, 75 mmol/L; IQR, 28-129 mmol/L; treatment effect, -41 mmol/L; IQR, -96-21 mmol/L; P = .12)”

   Animalsin dogs with heart diseasePO0.45-1 mg/kg/day5-7 daysn = 10

   Effect of the sodium glucose transporter-2 inhibitor dapagliflozin on urine and blood biomarkers in dogs with heart disease

   Journal of veterinary internal medicine·Mar 2, 2026

More on Dapagliflozin

1. Urine sodium is linked with a higher risk of abdominal obesity in humans (highest vs lowest quartile) (OR 4.68, 95% CI 2.44-8.96).

   “and abdominal obesity (OR 4.68, 95% CI 2.44-8.96) compared with the lowest quartile.”

   Humanshighest vs lowest quartilemalesn = 558

   Association between sodium intake, spot urine sodium concentration and obesity in Finnish adults: A population-based study

   Nutrition and health·Mar 5, 2026

More on Abdominal obesity

1. Urine sodium is linked with a higher risk of obesity in humans (highest vs lowest quartile) (OR 6.05, 95% CI 2.83-12.93).

   “Men in the highest quartile of urine sodium concentration had higher odds of general obesity (OR 6.05, 95% CI 2.83-12.93)”

   Humanshighest vs lowest quartilemalesn = 558

   Association between sodium intake, spot urine sodium concentration and obesity in Finnish adults: A population-based study

   Nutrition and health·Mar 5, 2026

More on Obesity