Roux-en-y gastric bypass

3 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Humans1
Animals1

Outcomes

Blood pressure

downin humans1downin rats1

1 study

Roux-en-y gastric bypass decreases blood pressure in rats (125.33±12.16 vs 182.00±11.61 mmHg SBP).
Animals8-week 8% high-salt diet8 weeks post-surgerymalesn = 30
Gastrointestinal metabolic surgery improves salt-sensitive hypertension via GLP-1-mediated inhibition of the RAS/NHE3 axis
Zhonghua xin xue guan bing za zhi13 Aug 2026
Roux-en-y gastric bypass decreases blood pressure in humans (133.26±16.48 vs 118.23±15.40 mmHg SBP, 83.16±12.44 vs 74.54±8.80 mmHg DBP).
Human trialn = 57
Gastrointestinal metabolic surgery improves salt-sensitive hypertension via GLP-1-mediated inhibition of the RAS/NHE3 axis
Zhonghua xin xue guan bing za zhi13 Aug 2026