Unhealthy lifestyle score

1. Unhealthy lifestyle score decreases femoral neck bone mineral density in humans.

   “MR analyses revealed causal relationships between UHLS and low grip strength, osteoarthritis, and reduced femoral neck bone mineral density.”

   HumansMendelian randomization analysisfemoral neck

   Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity

   Journal of bone and mineral metabolism·18 Aug 2025

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1. Unhealthy lifestyle score raises the risk of osteoarthritis in humans.

   “MR analyses revealed causal relationships between UHLS and low grip strength, osteoarthritis, and reduced femoral neck bone mineral density.”

   HumansMendelian randomization analysis

   Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity

   Journal of bone and mineral metabolism·18 Aug 2025

More on Osteoarthritis

1. Unhealthy lifestyle score raises the risk of low grip strength in humans.

   “MR analyses revealed causal relationships between UHLS and low grip strength, osteoarthritis, and reduced femoral neck bone mineral density.”

   HumansMendelian randomization analysis

   Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity

   Journal of bone and mineral metabolism·18 Aug 2025

1. Unhealthy lifestyle score is associated with fractures in humans (HR 1.059; 95% CI 1.048–1.069).

   “fracture (HR = 1.059; 95% CI: 1.048, 1.069)”

   Humansn = 396,037

   Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity

   Journal of bone and mineral metabolism·18 Aug 2025

More on Fractures

1. Unhealthy lifestyle score is associated with Phenotypic Age Acceleration in humans (0.408 per unit; 95% CI 0.394–0.422).

   “and phenotypic age (AA_PA) (0.408 per unit; 95% CI: 0.394, 0.422)”

   Humansn = 396,037

   Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity

   Journal of bone and mineral metabolism·18 Aug 2025

More on Phenotypic Age Acceleration

1. Unhealthy lifestyle score is associated with biological-age acceleration in humans (0.343 per unit; 95% CI 0.331–0.355).

   “Increasing UHLS was associated with elevated aging acceleration (AA) based on biological age (0.343 per unit; 95% CI: 0.331, 0.355)”

   Humansn = 396,037

   Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity

   Journal of bone and mineral metabolism·18 Aug 2025

More on Biological-age acceleration