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Two-marker cerebral small vessel disease burden

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Life's Essential 8

downin humans1OR 0.89

1 study

  1. Life's Essential 8 is associated with two-marker cerebral small vessel disease burden in humans (OR 0.89 per SD; 95% CI 0.87–0.91).

    “lower two-marker burden (OR 0.89 per SD; 0.87-0.91) without detected ethnoracial moderation.”

    HumansPer SD higher Life's Essential 8; no detected ethnoracial moderationbrain

    Brain small-vessel disease differed by ethnic and racial group

    medRxiv13 Oct 2026Preprint

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medRxiv

Brain small-vessel disease differed by ethnic and racial group

Black participants’ odds of greater combined disease burden were 1.66 times those of South Asian participants and 2.36 times those of Chinese participants.Black participants’ odds of greater combined disease burden were 1.66 times those of South Asian participants and 2.36 times those of Chinese participants.

Preprint: cross-sectional study of 44,982 peoplePopulations
Paper

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