Tumor grade

There are 4 papers on tumor grade in aging research: 3 observational studies in people, 1 in cells. The newest story, Oct 30, 2026: “Charts map brain oxygen extraction across human life”.

Biomarker

4 papers study it29 more mention it2 findings

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“Current combined menopausal hormone therapy (MHT) use was associated with lower grade”
Clarifying risk-factor associations with quantitative breast tumor features: a pooled analysis of 24 studiesJournal of the National Cancer Institute2026doi:10.1093/jnci/djag244
  • Humans3
  • Cells1

Associations

2

Hormone replacement therapy

downin humans1

1 study
  1. Hormone replacement therapy is associated with tumor grade in humans (current vs never users) (OR[grade 1] 3.37 (2.69-4.21) for current vs. never users; p-trend<0.001).

    “Current combined menopausal hormone therapy (MHT) use was associated with lower grade”

    Humanscurrent vs never userscombinedbreast tumor

    Clarifying risk-factor associations with quantitative breast tumor features: a pooled analysis of 24 studies

    Journal of the National Cancer Institute

More on Hormone replacement therapy

Patient age

downin humans1

1 study
  1. patient age is associated with tumor grade in humans (P=0.007).

    “A significant negative correlation between age and Ki-67 expression (P<0.0001) as well as grade of tumor (P=0.007) was identified.”

    Humansbreast tumor tissuen = 632

    Age-associated prognostic and predictive biomarkers in patients with breast cancer

    Oncology letters

Latest

Dec 2025: 1Jan 2026: 0Feb 2026: 1Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 3Aug 2026: 1Sep 2026: 0Oct 2026: 0Nov 2026: 07 papers in 12 months
medRxiv

Charts map brain oxygen extraction across human life

An observational study of 2,025 healthy people aged 0–93 found an age-related rise in extraction that slowed and plateaued later in life.An observational study of 2,025 healthy people aged 0–93 found an age-related rise in extraction that slowed and plateaued later in life.

Preprint: cross-sectional · 2,025 peopleBiomarkers

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